<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:587412c1-30ed-48c0-8f93-bd4510324912,g:010650c7-69ea-42d7-8ad9-bb03eff2783b-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.macomtech.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="simple" xlink:href="mtsi-20260102.xsd#CondensedConsolidatedBalanceSheetsUnaudited"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/CondensedConsolidatedBalanceSheetsUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_4d30fd65-16b8-47a9-a368-ed3e718999f5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_ce9661ff-d0ef-403d-b883-72790c714374" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_4d30fd65-16b8-47a9-a368-ed3e718999f5" xlink:to="loc_us-gaap_AccountsPayableCurrent_ce9661ff-d0ef-403d-b883-72790c714374" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtCurrent_82a2b5d5-c249-476e-8d82-e17379c61f4b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_4d30fd65-16b8-47a9-a368-ed3e718999f5" xlink:to="loc_us-gaap_LongTermDebtCurrent_82a2b5d5-c249-476e-8d82-e17379c61f4b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_755a6cdb-1d38-410e-976d-15ad1562b551" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_4d30fd65-16b8-47a9-a368-ed3e718999f5" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_755a6cdb-1d38-410e-976d-15ad1562b551" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_11429326-90f9-48f2-9926-189f678f9964" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_4d30fd65-16b8-47a9-a368-ed3e718999f5" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_11429326-90f9-48f2-9926-189f678f9964" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestments_5cb7eba8-c400-4526-b5b5-ffd5d152f189" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShortTermInvestments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:to="loc_us-gaap_ShortTermInvestments_5cb7eba8-c400-4526-b5b5-ffd5d152f189" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_1bf3da28-e3b8-4045-9f88-fe6d300d1c1c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:to="loc_us-gaap_InventoryNet_1bf3da28-e3b8-4045-9f88-fe6d300d1c1c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_7f11a5ae-19c2-4e5c-966f-b6a8f7968e6e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_7f11a5ae-19c2-4e5c-966f-b6a8f7968e6e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_4afad806-11ac-44fc-837e-ef7ae7384b45" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_4afad806-11ac-44fc-837e-ef7ae7384b45" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_da9d3cb6-bde5-4a2d-a307-e93974ef5ed7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_06e195c6-482a-4f0a-9b34-d1944272048c" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_da9d3cb6-bde5-4a2d-a307-e93974ef5ed7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_785ef6be-bcf2-4085-b4b6-3c93576eb090" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:to="loc_us-gaap_CommonStockValue_785ef6be-bcf2-4085-b4b6-3c93576eb090" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValue_d918985a-6a52-4278-859d-f67031893455" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockValue"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:to="loc_us-gaap_TreasuryStockValue_d918985a-6a52-4278-859d-f67031893455" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_59d7b618-f88f-4050-bbf6-8836eb6374ee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_59d7b618-f88f-4050-bbf6-8836eb6374ee" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_89611928-d061-4146-ac6f-90c121ccd090" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_89611928-d061-4146-ac6f-90c121ccd090" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_2624b034-cc7f-4514-b583-75637c8ef02e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_88a6fa25-3466-4b1a-b7c5-2c9309bce06d" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_2624b034-cc7f-4514-b583-75637c8ef02e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_0b66b48c-7865-4e03-826a-9ab4b84636d9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:to="loc_us-gaap_LiabilitiesCurrent_0b66b48c-7865-4e03-826a-9ab4b84636d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_7a6ec36f-f6e0-49d2-b4a9-00f91abe94b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_7a6ec36f-f6e0-49d2-b4a9-00f91abe94b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_FinancingObligationPropertyPlantAndEquipmentNoncurrent_649b94a0-9405-481b-8b73-84ebc3ac4caf" xlink:href="mtsi-20260102.xsd#mtsi_FinancingObligationPropertyPlantAndEquipmentNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:to="loc_mtsi_FinancingObligationPropertyPlantAndEquipmentNoncurrent_649b94a0-9405-481b-8b73-84ebc3ac4caf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_a93e8542-c15c-437f-9971-08f666f15261" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_a93e8542-c15c-437f-9971-08f666f15261" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_167ecb9f-5e4e-44a5-a2e0-d6d914566da4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_a70301ba-e385-44a7-bacd-d95ae0e16408" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_167ecb9f-5e4e-44a5-a2e0-d6d914566da4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_f896b6b0-7bf2-40ce-8e8f-8536a1d362d3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxAssetsNet"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_f896b6b0-7bf2-40ce-8e8f-8536a1d362d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_55a13f59-56eb-4c78-bce3-7d5ca53e7834" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_55a13f59-56eb-4c78-bce3-7d5ca53e7834" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3ecf5cc1-9a34-4241-a21b-c7f53d3e60fd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3ecf5cc1-9a34-4241-a21b-c7f53d3e60fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_fe54d531-37ef-4a49-8a3b-97cfd1791b33" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_Goodwill_fe54d531-37ef-4a49-8a3b-97cfd1791b33" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_17d927f5-0b82-4005-8422-9865780af677" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_17d927f5-0b82-4005-8422-9865780af677" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_a6ba96ec-fe6f-4d20-9605-886ad36b41b0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_bf10fbf1-0aaf-4e92-8a14-f205aefb1956" xlink:to="loc_us-gaap_AssetsCurrent_a6ba96ec-fe6f-4d20-9605-886ad36b41b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_ce858e7a-bdae-41eb-bc06-b40c746b7bba" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_a235c5e4-73bc-4650-b974-5e04aa806ce1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_ce858e7a-bdae-41eb-bc06-b40c746b7bba" xlink:to="loc_us-gaap_Liabilities_a235c5e4-73bc-4650-b974-5e04aa806ce1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_24195382-d25a-4af1-b7bf-a9a63f8b78e2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_ce858e7a-bdae-41eb-bc06-b40c746b7bba" xlink:to="loc_us-gaap_StockholdersEquity_24195382-d25a-4af1-b7bf-a9a63f8b78e2" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/CondensedConsolidatedStatementsofOperationsUnaudited" xlink:type="simple" xlink:href="mtsi-20260102.xsd#CondensedConsolidatedStatementsofOperationsUnaudited"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/CondensedConsolidatedStatementsofOperationsUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_7cbe5dbf-2325-4413-8c8f-0bc18134f090" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_0cd5705c-2ba9-4dbe-a1e2-b2be9cc47e0d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_7cbe5dbf-2325-4413-8c8f-0bc18134f090" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_0cd5705c-2ba9-4dbe-a1e2-b2be9cc47e0d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_a6548903-be71-42d7-aa40-5f7724161ab1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_7cbe5dbf-2325-4413-8c8f-0bc18134f090" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_a6548903-be71-42d7-aa40-5f7724161ab1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_ae7dc132-2c31-4c26-9df5-cf37fd9cf0ca" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_17965f0f-26b1-4a02-881d-da89d8d971a6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_ae7dc132-2c31-4c26-9df5-cf37fd9cf0ca" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_17965f0f-26b1-4a02-881d-da89d8d971a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_c4ce086e-7831-4f3d-9520-b80a47d3958d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_ae7dc132-2c31-4c26-9df5-cf37fd9cf0ca" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_c4ce086e-7831-4f3d-9520-b80a47d3958d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_2635bceb-968a-49ca-97da-294d1b13dc4f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_2119b953-8fd4-4d7a-8149-af9b755b0209" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_2635bceb-968a-49ca-97da-294d1b13dc4f" xlink:to="loc_us-gaap_GrossProfit_2119b953-8fd4-4d7a-8149-af9b755b0209" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_897488f9-be96-47b2-8402-cf37cc145bac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_2635bceb-968a-49ca-97da-294d1b13dc4f" xlink:to="loc_us-gaap_OperatingExpenses_897488f9-be96-47b2-8402-cf37cc145bac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_a92a9e90-2ed3-4f0d-999a-4b948df6bae8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_a8a914b6-0ed5-4fb8-979c-12fccf9d10f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_a92a9e90-2ed3-4f0d-999a-4b948df6bae8" xlink:to="loc_us-gaap_OperatingIncomeLoss_a8a914b6-0ed5-4fb8-979c-12fccf9d10f2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_e422bdff-dcad-4003-afb2-0e4e45ba5b3b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_a92a9e90-2ed3-4f0d-999a-4b948df6bae8" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_e422bdff-dcad-4003-afb2-0e4e45ba5b3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_cf02d60d-5921-4e87-98cb-241cd1fc38da" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NonoperatingIncomeExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_38263b84-7b1d-4d66-a0a8-60f65896a627" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_cf02d60d-5921-4e87-98cb-241cd1fc38da" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_38263b84-7b1d-4d66-a0a8-60f65896a627" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_e7990823-cc56-4aff-9f98-eb22e827cc26" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_cf02d60d-5921-4e87-98cb-241cd1fc38da" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_e7990823-cc56-4aff-9f98-eb22e827cc26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeOther_d472173f-3cb0-448f-ba97-12850320c92c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeOther"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NonoperatingIncomeExpense_cf02d60d-5921-4e87-98cb-241cd1fc38da" xlink:to="loc_us-gaap_InterestIncomeOther_d472173f-3cb0-448f-ba97-12850320c92c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_0dd7f6cb-2871-4da0-9daa-e24da5cc9fe3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_5735ca08-d59e-4166-b9df-474546c62852" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_0dd7f6cb-2871-4da0-9daa-e24da5cc9fe3" xlink:to="loc_us-gaap_Revenues_5735ca08-d59e-4166-b9df-474546c62852" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_42c53126-a543-4412-8d62-770bbf445d0c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_0dd7f6cb-2871-4da0-9daa-e24da5cc9fe3" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_42c53126-a543-4412-8d62-770bbf445d0c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/CondensedConsolidatedStatementsofComprehensiveLossIncomeUnaudited" xlink:type="simple" xlink:href="mtsi-20260102.xsd#CondensedConsolidatedStatementsofComprehensiveLossIncomeUnaudited"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/CondensedConsolidatedStatementsofComprehensiveLossIncomeUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_566850c0-5e06-4fc1-82bd-da80c7383a57" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_f00eda19-bfc8-4528-9cdb-cd9b5eaf2c4f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_566850c0-5e06-4fc1-82bd-da80c7383a57" xlink:to="loc_us-gaap_NetIncomeLoss_f00eda19-bfc8-4528-9cdb-cd9b5eaf2c4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_1d844fe4-8ff2-498a-8f98-26dd4d48d1f1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_566850c0-5e06-4fc1-82bd-da80c7383a57" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_1d844fe4-8ff2-498a-8f98-26dd4d48d1f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_6dc0598d-438b-4ba2-aa90-8e232ba89036" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax_fcc071fc-d497-4da4-a40e-1d9f81187808" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_6dc0598d-438b-4ba2-aa90-8e232ba89036" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax_fcc071fc-d497-4da4-a40e-1d9f81187808" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_78b847d3-4773-4096-a789-2de9a72baf5e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_6dc0598d-438b-4ba2-aa90-8e232ba89036" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_78b847d3-4773-4096-a789-2de9a72baf5e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/CondensedConsolidatedStatementsofCashFlowsUnaudited" xlink:type="simple" xlink:href="mtsi-20260102.xsd#CondensedConsolidatedStatementsofCashFlowsUnaudited"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/CondensedConsolidatedStatementsofCashFlowsUnaudited" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_62cde089-17d4-41d6-8c0e-65e04901c566" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_NetIncomeLoss_62cde089-17d4-41d6-8c0e-65e04901c566" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_bfcc51a9-57ee-4f20-92ca-79fc2d214e37" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_bfcc51a9-57ee-4f20-92ca-79fc2d214e37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_a489e76e-c19b-4c7c-8cfa-e069369d6f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_ShareBasedCompensation_a489e76e-c19b-4c7c-8cfa-e069369d6f2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes_0fb1823e-4405-460d-8588-c607f068fa96" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInDeferredIncomeTaxes"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes_0fb1823e-4405-460d-8588-c607f068fa96" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_9d2d51ea-68a0-472f-892d-754ffd092f62" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_9d2d51ea-68a0-472f-892d-754ffd092f62" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_AmortizationOnMarketableSecuritiesNet_effa8f92-e6db-4e09-b978-36aacbb94637" xlink:href="mtsi-20260102.xsd#mtsi_AmortizationOnMarketableSecuritiesNet"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_mtsi_AmortizationOnMarketableSecuritiesNet_effa8f92-e6db-4e09-b978-36aacbb94637" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_8dae9fb4-3a09-4aa2-b17b-86760e693920" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_8dae9fb4-3a09-4aa2-b17b-86760e693920" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_d57b4fa6-b72f-4e59-b5c8-f307b65070ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_d57b4fa6-b72f-4e59-b5c8-f307b65070ac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_7299f520-9af2-4834-b020-53b8f76d1aa8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_7299f520-9af2-4834-b020-53b8f76d1aa8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_c9043fab-24a1-4de6-bbbd-565ad395f959" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_c9043fab-24a1-4de6-bbbd-565ad395f959" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_4d6a4333-75ff-4d70-999b-2dd829b96e7e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_4d6a4333-75ff-4d70-999b-2dd829b96e7e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_1b0f6d38-4a4e-4500-a247-5f2f634b9818" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_1b0f6d38-4a4e-4500-a247-5f2f634b9818" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_5ee3d3ec-b69a-4dc9-8109-5d1784e40a56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_848e8345-0141-4991-b603-7f904cbc49c3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_5ee3d3ec-b69a-4dc9-8109-5d1784e40a56" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_58110ade-a379-4bb4-8f3b-356a81cd07e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_58110ade-a379-4bb4-8f3b-356a81cd07e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_2ef76618-9ff4-430f-80f2-d52c4b9a623d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_2ef76618-9ff4-430f-80f2-d52c4b9a623d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForSoftware_4a37a57b-eb36-4b58-82c9-98b3965d98e6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForSoftware"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_PaymentsForSoftware_4a37a57b-eb36-4b58-82c9-98b3965d98e6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments_cd77150e-a376-4971-b258-ec6e64320479" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_ProceedsFromSaleMaturityAndCollectionsOfInvestments_cd77150e-a376-4971-b258-ec6e64320479" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireInvestments_99d5320d-9ae5-402b-971e-42914d192e94" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireInvestments"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_PaymentsToAcquireInvestments_99d5320d-9ae5-402b-971e-42914d192e94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_f187dc37-38e8-4df9-9562-44950f11f5f0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_5ac140a7-9733-4497-b901-08e9dff36903" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_f187dc37-38e8-4df9-9562-44950f11f5f0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9ff9cbdc-679b-4c96-96c3-c05608506f2c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b84da86e-ff92-4315-b47f-5ebe53c7bf86" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9ff9cbdc-679b-4c96-96c3-c05608506f2c" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b84da86e-ff92-4315-b47f-5ebe53c7bf86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_aad72feb-4572-4d09-b3e3-c5774bb5dd26" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9ff9cbdc-679b-4c96-96c3-c05608506f2c" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_aad72feb-4572-4d09-b3e3-c5774bb5dd26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_def14689-5bb9-4d4d-8ef0-2c12cc1d3fc3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9ff9cbdc-679b-4c96-96c3-c05608506f2c" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_def14689-5bb9-4d4d-8ef0-2c12cc1d3fc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_e5808576-65ee-4641-a631-508cd800fe71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9ff9cbdc-679b-4c96-96c3-c05608506f2c" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_e5808576-65ee-4641-a631-508cd800fe71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromConvertibleDebt_f67ba9df-e547-41ad-b858-7625c9ac577e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromConvertibleDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_us-gaap_ProceedsFromConvertibleDebt_f67ba9df-e547-41ad-b858-7625c9ac577e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_ProceedsFromFinancingArrangement_5b331d37-c05b-4f3a-86f9-44a9c71fecc8" xlink:href="mtsi-20260102.xsd#mtsi_ProceedsFromFinancingArrangement"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_mtsi_ProceedsFromFinancingArrangement_5b331d37-c05b-4f3a-86f9-44a9c71fecc8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfNotesPayable_27a183b3-a971-4b79-a72e-c5a0da7e6c8b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfNotesPayable"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_us-gaap_RepaymentsOfNotesPayable_27a183b3-a971-4b79-a72e-c5a0da7e6c8b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_83494202-e1e2-4fcf-bc63-bc4dff79aa55" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_83494202-e1e2-4fcf-bc63-bc4dff79aa55" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions_8454e6b1-3551-4dbc-9977-9a3f6a4d1ffd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions_8454e6b1-3551-4dbc-9977-9a3f6a4d1ffd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_4454c8df-b7f5-4bcd-a4a6-0f42ab8a4d83" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_eb5a8c76-0e9e-4007-9164-b01b64393ac0" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_4454c8df-b7f5-4bcd-a4a6-0f42ab8a4d83" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INVESTMENTSSummaryofAvailableforSaleInvestmentsDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INVESTMENTSSummaryofAvailableforSaleInvestmentsDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INVESTMENTSSummaryofAvailableforSaleInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_b6d3e515-f121-49b4-aa6c-a5048c851706" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_b58093ed-702d-40bf-900b-fd076f8d3235" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_b6d3e515-f121-49b4-aa6c-a5048c851706" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_b58093ed-702d-40bf-900b-fd076f8d3235" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_eed8e8ec-8cba-4df6-9f71-8170126f2804" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_b6d3e515-f121-49b4-aa6c-a5048c851706" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_eed8e8ec-8cba-4df6-9f71-8170126f2804" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1e4583c2-2573-436f-b8b1-5aaf413d1bae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_b6d3e515-f121-49b4-aa6c-a5048c851706" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_1e4583c2-2573-436f-b8b1-5aaf413d1bae" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INVESTMENTSSummaryofContractualMaturitiesofInvestmentsDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INVESTMENTSSummaryofContractualMaturitiesofInvestmentsDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INVESTMENTSSummaryofContractualMaturitiesofInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_3707be5e-57a7-498e-9187-f5e608d0f112" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_1f0ac8a6-71eb-46cf-9ebd-bd284050e3cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_3707be5e-57a7-498e-9187-f5e608d0f112" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_1f0ac8a6-71eb-46cf-9ebd-bd284050e3cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesNoncurrent_184c1fc1-2afa-40cf-b1fd-293185d16a60" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_3707be5e-57a7-498e-9187-f5e608d0f112" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesNoncurrent_184c1fc1-2afa-40cf-b1fd-293185d16a60" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INVENTORIESDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INVENTORIESDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INVENTORIESDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_2970f82f-0948-490c-adb8-3474dd1229cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_92f47321-6e32-4c45-a1ab-2a57b5e02c08" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_2970f82f-0948-490c-adb8-3474dd1229cb" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_92f47321-6e32-4c45-a1ab-2a57b5e02c08" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_93d1655f-dda7-4e1a-930c-e95c0df8952c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_2970f82f-0948-490c-adb8-3474dd1229cb" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_93d1655f-dda7-4e1a-930c-e95c0df8952c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_1ff93e72-e18c-481b-911a-fb8f9f5fb832" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InventoryNet_2970f82f-0948-490c-adb8-3474dd1229cb" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_1ff93e72-e18c-481b-911a-fb8f9f5fb832" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/PROPERTYANDEQUIPMENTComponentsofPropertyPlantandEquipmentDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#PROPERTYANDEQUIPMENTComponentsofPropertyPlantandEquipmentDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/PROPERTYANDEQUIPMENTComponentsofPropertyPlantandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_dcffd30a-274f-4d22-8c7e-3dc75fe08c1f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_3a781164-a53f-4263-8a33-41864ecd4d7c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_dcffd30a-274f-4d22-8c7e-3dc75fe08c1f" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_3a781164-a53f-4263-8a33-41864ecd4d7c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_dfdb79f4-f861-4f0d-8749-7c0613d015ef" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_dcffd30a-274f-4d22-8c7e-3dc75fe08c1f" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_dfdb79f4-f861-4f0d-8749-7c0613d015ef" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofIntangibleAssetsDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INTANGIBLEASSETSSummaryofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_90006cb8-851e-442e-b331-a719ab43de45" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_70bdd069-391e-4294-bf95-a6fded96d0d2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_90006cb8-851e-442e-b331-a719ab43de45" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_70bdd069-391e-4294-bf95-a6fded96d0d2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_db86272b-644c-4af9-b971-5e1b1385dc6c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_90006cb8-851e-442e-b331-a719ab43de45" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_db86272b-644c-4af9-b971-5e1b1385dc6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_e6cc783e-a4e3-4388-9efe-9fcedd8141ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_90006cb8-851e-442e-b331-a719ab43de45" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_e6cc783e-a4e3-4388-9efe-9fcedd8141ad" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofActivityinIntangibleAssetsandGoodwillDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INTANGIBLEASSETSSummaryofActivityinIntangibleAssetsandGoodwillDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofActivityinIntangibleAssetsandGoodwillDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_a3cdcfb4-03d2-447c-a5df-151ef87991a5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_7c56e34a-07db-48f2-90ed-2e576b78d935" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_a3cdcfb4-03d2-447c-a5df-151ef87991a5" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_7c56e34a-07db-48f2-90ed-2e576b78d935" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_5d9364cb-fc8a-4a61-b048-89aa9802d497" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_a3cdcfb4-03d2-447c-a5df-151ef87991a5" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_5d9364cb-fc8a-4a61-b048-89aa9802d497" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_b3108ed5-3085-49ea-824f-ee38a631ba64" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_2ff9e9b4-4428-495b-8788-5db326b5250a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_b3108ed5-3085-49ea-824f-ee38a631ba64" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_2ff9e9b4-4428-495b-8788-5db326b5250a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_d80dc3e5-a5cc-420d-ac4f-e4757cff4652" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_b3108ed5-3085-49ea-824f-ee38a631ba64" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_d80dc3e5-a5cc-420d-ac4f-e4757cff4652" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofEstimatedAmortizationofIntangibleAssetsDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#INTANGIBLEASSETSSummaryofEstimatedAmortizationofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/INTANGIBLEASSETSSummaryofEstimatedAmortizationofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_ec541343-f10d-4d8e-a7d8-625d23d82c04" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_ec541343-f10d-4d8e-a7d8-625d23d82c04" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_167d900b-b474-4c89-9a15-393fcc564ede" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_167d900b-b474-4c89-9a15-393fcc564ede" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_ae2f546b-1c02-4403-8665-838b1a3d12be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_ae2f546b-1c02-4403-8665-838b1a3d12be" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_1b64c78a-c628-458d-9a46-46c16069bf29" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_1b64c78a-c628-458d-9a46-46c16069bf29" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_c771bcc7-a0b7-446a-a052-ec3aa97883f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_c771bcc7-a0b7-446a-a052-ec3aa97883f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_be59dca1-6072-463c-b5f5-d0bd39599ed3" xlink:href="mtsi-20260102.xsd#mtsi_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_dfe4986b-0a9c-446c-8b71-aac9dd15f6e7" xlink:to="loc_mtsi_FiniteLivedIntangibleAssetExpectedAmortizationAfterYearFour_be59dca1-6072-463c-b5f5-d0bd39599ed3" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/AccruedLiabilitiesScheduleofAccruedLiabilitiesDetail" xlink:type="simple" xlink:href="mtsi-20260102.xsd#AccruedLiabilitiesScheduleofAccruedLiabilitiesDetail"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/AccruedLiabilitiesScheduleofAccruedLiabilitiesDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019c0082-86ef-7d6e-954d-6ad5da9af1b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019c0082-86ef-7d6e-954d-6ad5da9af1b3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_019c0082-86ef-7697-a351-299c012a0371" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_019c0082-86ef-7697-a351-299c012a0371" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredRevenue_019c0082-86ef-7188-8688-3bfc42ce51f8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredRevenue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:to="loc_us-gaap_DeferredRevenue_019c0082-86ef-7188-8688-3bfc42ce51f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_InternalUseSoftwareAccrual_019c0082-86ef-779c-acc7-c947d4825376" xlink:href="mtsi-20260102.xsd#mtsi_InternalUseSoftwareAccrual"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:to="loc_mtsi_InternalUseSoftwareAccrual_019c0082-86ef-779c-acc7-c947d4825376" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_019c0082-86ef-7012-8ce0-93162f24d7fc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccruedLiabilitiesCurrent_019c0082-86ef-7a17-971f-9e530654368c" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_019c0082-86ef-7012-8ce0-93162f24d7fc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/EARNINGSPERSHAREDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#EARNINGSPERSHAREDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/EARNINGSPERSHAREDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_99e25b6c-98d5-4995-b73f-b0b9077a7c21" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_483c3b58-2ebe-46de-8d3f-9464bf896b8a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_99e25b6c-98d5-4995-b73f-b0b9077a7c21" xlink:to="loc_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment_483c3b58-2ebe-46de-8d3f-9464bf896b8a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_51880ee4-cc61-4592-9bd8-10913e8c6f74" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_99e25b6c-98d5-4995-b73f-b0b9077a7c21" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_51880ee4-cc61-4592-9bd8-10913e8c6f74" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.macomtech.com/role/SEGMENTREPORTINGGEOGRAPHICANDSIGNIFICANTCUSTOMERINFORMATIONSegmentDetails" xlink:type="simple" xlink:href="mtsi-20260102.xsd#SEGMENTREPORTINGGEOGRAPHICANDSIGNIFICANTCUSTOMERINFORMATIONSegmentDetails"/>
  <link:calculationLink xlink:role="http://www.macomtech.com/role/SEGMENTREPORTINGGEOGRAPHICANDSIGNIFICANTCUSTOMERINFORMATIONSegmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Revenues_019bfc9a-3f31-7f27-b3fa-0fd5fc9f4881" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Revenues"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_us-gaap_Revenues_019bfc9a-3f31-7f27-b3fa-0fd5fc9f4881" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_CostOfProductAndServiceSoldAdjusted_019bfc9a-3f31-7e7e-b019-5d82a109ec73" xlink:href="mtsi-20260102.xsd#mtsi_CostOfProductAndServiceSoldAdjusted"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_mtsi_CostOfProductAndServiceSoldAdjusted_019bfc9a-3f31-7e7e-b019-5d82a109ec73" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_ResearchAndDevelopmentExpenseAdjusted_019bfc9a-3f31-78ac-8b7b-1082dcf39afb" xlink:href="mtsi-20260102.xsd#mtsi_ResearchAndDevelopmentExpenseAdjusted"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_mtsi_ResearchAndDevelopmentExpenseAdjusted_019bfc9a-3f31-78ac-8b7b-1082dcf39afb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_mtsi_SellingGeneralAndAdministrativeExpenseAdjusted_019bfc9a-3f31-7208-9686-84d978f11464" xlink:href="mtsi-20260102.xsd#mtsi_SellingGeneralAndAdministrativeExpenseAdjusted"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_mtsi_SellingGeneralAndAdministrativeExpenseAdjusted_019bfc9a-3f31-7208-9686-84d978f11464" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_019bfc9a-3f31-700a-b458-6e2f05e98a17" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LaborAndRelatedExpense"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_us-gaap_LaborAndRelatedExpense_019bfc9a-3f31-700a-b458-6e2f05e98a17" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_019bfc9a-3f31-7d94-8f47-d3622284c00c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_019bfc9a-3f31-7d94-8f47-d3622284c00c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_019bfc9a-3f31-7154-bf8c-b22e00eff90b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationIntegrationRelatedCosts"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019bfc9a-3f31-72b7-9977-313bfc6225fb" xlink:to="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_019bfc9a-3f31-7154-bf8c-b22e00eff90b" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
